Paroex Chlorhexidine 0.12% Mouthwash Without Alcohol, 300 ml

Product Information

Your dentist has prescribed Paroex ® to treat your gingivitis - to help reduce the redness and swelling of your gums, and also to help you control any gum bleeding. If you develop allergic symptoms such as skin rash, itch, generalized swelling, breathing difficulties, light headedness, rapid heart rate, upset stomach or diarrhea, seek medical attention immediately. Paroex® should not be used by persons who have a sensitivity to it or its components.

In addition to medications, there are a few natural remedies that can treat oral thrush and prevent episodes of oral thrush from recurring. Some include: Following use of a 0.12% topical oral solution of chlorhexidine gluconate as a mouthwash or oral rinse, approximately 30% of drug is retained in oral cavity. The drug is bound to phosphate groups principally on coatings of mucous membrane surfaces and gradually released into oral fluids for up to 24 hours. Topical oral solution: Advise patients that the solution may taste bitter and can affect how foods and beverages taste; this usually becomes less noticeable with continued use. Using the solution after meals may avoid taste interference. Use Paroex ® regularly, as directed by your dentist, in addition to daily brushing and flossing. Spit out after use. Paroex ® should not be swallowed. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.Paroex ® can cause staining of oral surfaces, such as tooth surfaces, restorations, and the dorsum of the tongue. Not all patients will experience a visually significant increase in toothstaining. In clinical testing, 56% of chlorhexidine gluconate oral rinse users exhibited a measurable increase in facial anterior stain, compared to 35% of control users after six months; 15% of chlorhexidine gluconate oral rinse users developed what was judged to be heavy stain, compared to 1% of control users after six months. Stain will be more pronounced in patients who have heavier accumulations of unremoved plaque. Stain resulting from use of Paroex ® does not adversely affect health of the gingivae or other oral tissues. Stain can be removed from most tooth surfaces by conventional professional prophylactic techniques. Additional time may be required to complete the prophylaxis. Discretion should be used when prescribing to patients with anterior facial restorations with rough surfaces or margins. If natural stain cannot be removed from these surfaces by a dental prophylaxis, patients should be excluded from Paroex ® treatment if permanent discoloration is unacceptable. Stain in these areas may be difficult to remove by dental prophylaxis and on rare occasions may necessitate replacement of these restorations. Following oral administration † of a single 300-mg dose, the drug is excreted in feces via biliary elimination (90%) and urine (<1%). Stability Storage Oral, Topical Use Only Solution Tooth/ tongue staining, increased tartar, mouth/throat irritation, dry mouth, and change in taste of food/drinks may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Oral irritation and local allergy-type symptoms have been spontaneously reported as side effects associated with use of chlorhexidine gluconate rinse. The following oral mucosal side effects were reported during placebo-controlled adult clinical trails: aphthous ulcer, grossly obvious gingivitis, trauma, ulceration, erythema, desquamation, coated tongue, keratinization, geographic tongue, mucocele, and short frenum. Each occurred at a frequency of less than 1.0%. Among post marketing reports, the most frequently reported oral mucosal symptoms associated with chlorhexidine gluconate oral rinse are stomatitis, gingivits, glossitis, ulcer, dry mouth, hypesthesia, glossal edema, and paresthesia. Minor irritation and superficial desquamation of the oral mucosa have been noted in patients using chlorhexidine gluconate oral rinse. There have been cases of parotid gland swelling and inflammation of the salivary glands (sialadenitis) reported in patients using chlorhexidine gluconate oral rinse. Sunstar Americas is voluntarily recalling its Paroex Chlorhexidine Gluconate Oral Rinse USP 0.12% products bearing an expiration date between December 31, 2020, and September 30, 2022, due to possible contamination with the bacteria Burkholderia lata.

Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Reproduction studies have been performed in rats and rabbits at chlorhexidine gluconate doses up to 300 mg/kg/day and 40 mg/kg/day, respectively, and have not revealed evidence of harm to fetus. However, adequate and well-controlled studies in pregnant women have not been done. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Nursing Mothers Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations.

Interaction

Take vitamin C: Vitamin C can encourage white blood cell production and protect your body against infection. Increasing your intake of this vitamin may help boost your body’s ability to beat the infection. Store mouthwash away from direct sunlight in a dry, cool place. If you usually forget to use mouthwash and want to get into the habit, place it in a visible location. Subgingival insert: No adequate and controlled studies to date in pregnant women; use during pregnancy only when clearly needed. Lactation Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding. Drug Interactions Serious allergic reactions, including fatal anaphylaxis, reported rarely with topical chlorhexidine preparations used on the skin (e.g., solutions, washes, sponges, swabs), including OTC topical preparations.